In 1992, Russo was hired by the World Wrestling Federation for WWF Magazine and would later become an editor in 1994 under the pseudonym of Vic Venom. Russo would eventually leave the WWF in 1999.
On the April 10, 2000 edition of WCW Monday Nitro, Vince Russo was introduced to World Championship Wrestling as an on-screen antagonist authority figure. Notable storyline points his character was involved with include The New Blood versus The Millionaire's Club; his feud with Ric Flair, where he and David Flair were involved with shaving Ric Flair's hair; his feud with Goldberg; and his short reign as WCW World Champion. He also worked with Miss Elizabeth.
At Bash at the Beach 2000, Russo was involved in an incident with Hulk Hogan where Hogan was booked to lose a match against reigning world champion Jeff Jarrett. Jarrett would literally lie down for Hogan, with Hogan scoring the pinfall victory by placing his foot on Jarrett's chest. Russo would come out later in the broadcast to nullify the result of the match, as he publicly fired Hogan. This action restored the title to Jarrett, which set up a new title match between Jarrett and Booker T, with the latter winning the match and the title.
In September 2000, Russo entered into an angle with Ric Flair. The angle notably included Russo sending cops to the ring to arrest Flair during the wedding between Stacy Keibler and Flair's son David. Once WCW was bought out by the WWF, Russo left the company.