Spicolli debuted in 1988, working as a jobber for the World Wrestling Federation. His occasional appearances saw him lose to many of the WWF's top stars, though he did register two victories in 1993, defeating The White Knight and The Lightning Kid. He also picked up a victory on March 13, 1995 over Greg Davis, his last appearance before being repackaged.
In April 1995, the WWF repackaged Spicolli as Rad Radford, a fan of grunge. He worked an angle with the Bodydonnas, wanting to join (despite his comparatively poorly toned body) and was eventually admitted as a "Bodydonna-in-training". This lasted until Survivor Series, when he was thrown out of the group because his physique was not good enough. Spicolli achieved little success as Radford, rarely getting victories over other name talent. He would be released in early 1996.
Spicolli joined Extreme Championship Wrestling in July 1996 as a face. He later turned heel and feuded with Tommy Dreamer. He left the company not long after.
Spicolli signed with WCW in late 1997 and became the lackey of New World Order member Scott Hall, dubbing himself "The Real Innovator" in order to mock Tommy Dreamer (known by the nickname "The Innovator of Violence"). Spicolli later began commentating during matches. Hall and Spicolli soon feuded with Larry Zbyszko, with Spicolli stealing Zbyszko's golf clubs, bringing them to the ring, and breaking them over his knee while Hall made sarcastic comments on the mic. This resulted in a match between Spicolli and Zbyszko being booked for SuperBrawl VIII on February 22, 1998. However, the match never took place due to Louie Spicolli's death one week before the match.
Spicolli passed away on February 15, 1998.