Nakano wrestled for the World Wrestling Federation in 1986, teaming with Dump Matsumoto against the team of Velvet McIntyre and Dawn Marie Johnston.
In 1994, she competed for the World Wrestling Federation (WWF) once again. Debuting as an associate of Luna Vachon, Nakano competed against the WWF Women's Champion, Alundra Blayze in August 1994 at SummerSlam, but failed to win the title. Nakano eventually defeated Blayze for the title on November 20, 1994 in Tokyo. Nakano held the title for approximately five months, until losing it back to Blayze on the April 3, 1995 episode of Raw ending her reign at 134 days. She was released from the company soon thereafter.
In 1995, she competed at World Championship Wrestling (WCW)'s World War 3 pay-per-view event, teaming with Akira Hokuto to defeat the team of Cutie Suzuki and Mayumi Ozaki. Nakano, with Sonny Onoo as her manager, continued her feud with Alundra Blayze, who was now known as Madusa, at WCW's Hog Wild event in August 1996; Madusa defeated Nakano in the match with the stipulation that she was then allowed to destroy Nakano's motorcycle.
On March 6, 2024, Nakano was announced as an inductee into the WWE Hall of Fame class of 2024.