In 1991 and 1992, Guido made a few appearances for the World Wrestling Federation as a jobber under the ring name Mike Fury. He lost to such stars as The British Bulldog, The Warlord, Tito Santana and Bret Hart.
He first joined the Full Blooded Italians in the original ECW at Heatwave 1996, introduced as Little Guido's "little" brother, Big Guido. He accompanied the stable members to the ring, and sporadically fought actual matches.
Guido reappeared on World Wrestling Entertainment's ECW brand's One Night Stand on June 12, 2005 accompanying the Full Blooded Italians to the ring. Big Guido then reappeared on ECW on June 11, 2006 during ECW One Night Stand alongside Tony Mamaluke and Little Guido. On the June 13 edition of ECW, Big Guido took part in the hardcore battle royal and was eliminated by The Big Show, but helped Sabu eliminate Big Show.